
Lifestyle interventions to prevent diabetes: Long-term, intensive, individual counseling programs
Healthcare: Obesity and DiabetesBenefit-cost methods last updated December 2024. Literature review updated February 2017.
ALL |
META-ANALYSIS |
CITATIONS |
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| Benefit-Cost Summary Statistics Per Participant | ||||||
|---|---|---|---|---|---|---|
| Benefits to: | ||||||
| Taxpayers | $10,945 | Benefits minus costs | $33,012 | |||
| Participants | $17,339 | Benefit to cost ratio | $8.14 | |||
| Others | $7,997 | Chance the program will produce | ||||
| Indirect | $1,356 | benefits greater than the costs | 100% | |||
| Total benefits | $37,638 | |||||
| Net program cost | ($4,626) | |||||
| Benefits minus cost | $33,012 | |||||
| Meta-Analysis of Program Effects | ||||||||||||
| Outcomes measured | Treatment age | No. of effect sizes | Treatment N | Effect sizes (ES) and standard errors (SE) used in the benefit-cost analysis | Unadjusted effect size (random effects model) | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| First time ES is estimated | Second time ES is estimated | |||||||||||
| ES | SE | Age | ES | SE | Age | ES | p-value | |||||
Diabetes incidence Clinical diagnosis of type 2 diabetes. |
50 | 2 | 1344 | -0.533 | 0.098 | 53 | -0.255 | 0.077 | 60 | -0.533 | 0.001 | |
Weight change Loss or gain of total body weight |
50 | 2 | 1344 | -0.298 | 0.052 | 53 | 0.000 | 0.054 | 60 | -0.298 | 0.001 | |
Fasting glucose^ Fasting Plasma Glucose (FPG). |
50 | 2 | 1344 | -0.453 | 0.053 | 50 | n/a | n/a | n/a | -0.453 | 0.001 | |
| Detailed Monetary Benefit Estimates Per Participant | ||||||
| Affected outcome: | Resulting benefits:1 | Benefits accrue to: | ||||
|---|---|---|---|---|---|---|
| Taxpayers | Participants | Others2 | Indirect3 | Total |
||
| Diabetes incidence | Labor market earnings associated with diabetes | $6,419 | $15,122 | $0 | $0 | $21,541 |
| Health care associated with diabetes | $4,519 | $2,200 | $7,997 | $2,278 | $16,993 | |
| Mortality associated with diabetes | $8 | $18 | $0 | $1,391 | $1,417 | |
| Program cost | Adjustment for deadweight cost of program | $0 | $0 | $0 | ($2,313) | ($2,313) |
| Totals | $10,945 | $17,339 | $7,997 | $1,356 | $37,638 | |
| Detailed Annual Cost Estimates Per Participant | ||||
| Annual cost | Year dollars | Summary | ||
|---|---|---|---|---|
| Program costs | $1,287 | 2014 | Present value of net program costs (in 2023 dollars) | ($4,626) |
| Comparison costs | $0 | 2014 | Cost range (+ or -) | 10% |
Benefits Minus Costs |
Benefits by Perspective |
Taxpayer Benefits by Source of Value |
| Benefits Minus Costs Over Time (Cumulative Discounted Dollars) |
| The graph above illustrates the estimated cumulative net benefits per-participant for the first fifty years beyond the initial investment in the program. We present these cash flows in discounted dollars. If the dollars are negative (bars below $0 line), the cumulative benefits do not outweigh the cost of the program up to that point in time. The program breaks even when the dollars reach $0. At this point, the total benefits to participants, taxpayers, and others, are equal to the cost of the program. If the dollars are above $0, the benefits of the program exceed the initial investment. |
Citations Used in the Meta-Analysis
Haffner, S., Temprosa, M., Crandall, J., Fowler, S., Goldberg, R., Horton, E., Marcovina, S., ... Diabetes Prevention Program Research Group. (2005). Intensive lifestyle intervention or metformin on inflammation and coagulation in participants with impaired glucose tolerance. Diabetes, 54(5), 1566-72.
Knowler, W.C., Barrett-Connor, E., Fowler, S.E., Hamman, R.F., Lachin, J.M., Walker, E.A., Nathan, D.M., ... Diabetes Prevention Program Research Group. (2002). Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. The New England Journal of Medicine, 346(6), 393-403.
Lindstrom, J., Eriksson, J.G., Valle, T.T., Aunola, S., Cepaitis, Z., Hakumaki, M., Hamalainen, H., ... Tuomilehto, J. (2003). Prevention of diabetes mellitus in subjects with impaired glucose tolerance in the Finnish Diabetes Prevention Study: Results from a randomized clinical trial. Journal of the American Society of Nephrology, 14, 2, S108-S113.
Tuomilehto, J., Lindstro¨m, J., Eriksson, J.G., Valle, T.T., Ha¨ma¨la¨inen, H., Ilanne-Parikka, P., Keina¨nen-Kiukaanniemi, S., ... Finnish Diabetes Prevention Study Group. (2001). Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. The New England Journal of Medicine, 344(18), 1343-50.