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The Washington State Institute for Public Policy's (WSIPP) Board of Directors authorized WSIPP to work on a joint project with the MacArthur Foundation and the Pew Charitable Trusts to extend WSIPP’s benefit-cost analysis to certain health care topics. The Pew-MacArthur Results First Initiative identified diabetes prevention as an important health care issue for states. One important goal is to determine whether diabetes prevention policies can help states control Medicaid and other health care costs. We reviewed credible research studies from the United States and elsewhere to determine whether lifestyle programs can achieve these results. We find that, on average, the programs have significant effects on diabetes incidence, weight loss, and certain risk factors for cardiovascular disease.