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Initiative 502 (I-502) legalized recreational cannabis for adults in Washington State. The law directs a portion of cannabis revenues to be spent on substance abuse prevention and treatment services that have been demonstrated to be effective. Specifically, state law requires at least 85% of programs funded by cannabis revenues to be evidence-based or research-based, and up to 15% to be promising practices. In this inventory, we rate the research evidence for programs intended for the prevention or treatment of youth substance use, and we identify those specifically effective for reducing marijuana use. The 2018 Washington State Legislature directed WSIPP to update this inventory. This is the fourth update in the series.